Links
This table provides detailed links and descriptions with respect to previously developed servers or softwares for protease substrate cleavage sites prediction.
Note that among them, three are general cleavage site prediction servers (PeptideCutter, PoPS and SitePrediction), Cascleave is family-specific servers that were specifically designed to model and predict the substrate specificity for a particular protease.
| Predictors | Description | Features |
|---|---|---|
| PeptideCutter | Predict potential cleavage sites cleaved by proteases or chemicals | Amino acid occurrence |
| PoPS | Prediction of protease specificity | Amino acid occurrence, Position-specific scoring matrices (PSSM), predicted structure information such as substrate secondary structure and solvent accessibility |
| Cascleave | Predict substrate cleavage site of caspases | Multiple sequential and structural features including local amino acid sequence profile, predicted solvent accessibility and native disorder features |
| SitePrediction | Predicting the cleavage of proteinase substrastes | Amino acid occurrence, 'PEST' sequences, and structural information such as secondary structure and solvent accessibility |
